During my academic studies I obtained a degree in Biology and a master’s degree on Biochemistry, Molecular Biology and Biomedicine at Complutense University of Madrid (2012-2017). From my second year as an undergraduate on, I worked in the Department of Biochemistry and Molecular Biology. I participated in a translational project aimed at elucidating the role of a neurotrophic factor, Midkine, in the tumorigenic capacity of Glioma Stem-like Cells, as well as the antitumoral effect of cannabinoids in the establishment and growth of brain tumors in mouse models and in patient-derived tumor samples. This 4-year internship granted me two publications on autophagy and glioblastomas and hands-on experience in wet lab activities. After this, I joined the Cell Division and Cancer Group at CNIO in 2017 to pursue my PhD studies under the supervision of Dr. Marcos Malumbres.
The main thesis projects I’ve been developing are aimed to:
i) understand the mechanisms of asymmetric cell division of neural progenitors during mammalian brain development and their potential relationship with the regulation of the mitotic machinery
ii) assess the consequences of cell cycle de-regulation in the etiology of certain neurodevelopmental syndromes, including primary microcephaly
iii) explore the putative role of microRNAs and cell cycle regulators in the regulation of cell totipotency and pluripotency in early pre-implantational stages and their impact in early developmental scenarios, stem cell epigenetics and regenerative medicine.